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Another important issue in biosensors is to design a simple
2020-12-15

Another important issue in biosensors is to design a simple and potable detection strategy to meet the requirement of the point-of-care (POC) test applications. According to the recent research, by using invertase thiotepa for hydrolyzing sucrose into glucose, the range of personal glucometer has be
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Collagen X is a homotrimeric molecule
2020-12-14

Collagen X is a homotrimeric molecule of three α1(X) chains (Mr 59 kDa) comprising a 45 kDa triple-helical domain flanked by an N-terminal (NC2) and a larger C-terminal (NC1) non-collagenous domains (Shen, 2005). In the hypertrophic ECM, collagen X most likely forms an extended hexagonal network, as
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br Materials and methods br Results br Discussion Recently
2020-12-14

Materials and methods Results Discussion Recently, circRNAs have been found to play important diagnostic or prognostic roles in different tumors. For example, aberrant expression levels of different circRNAs are found in ovarian cancer, lung cancer, renal cancer, gastric cancer and particip
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br Results and discussion A systematic search for
2020-12-14

Results and discussion A systematic search for genes encoding H+-PPases was carried out by PCR using genomic DNA from a wide range of protozoa as templates and degenerate oligonucleotides, designed from amino fauc domains conserved in H+-PPases of higher plants and the proteobacterium R. rubrum,
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DAPK is involved in the p
2020-12-14

DAPK-1 is involved in the p53 dependent apoptotic pathway and it is a mediator of γ-interferon induced apoptosis. DAPK-1 is also involved in other death signaling pathways (tumor necrosis factor-α, CD95 and transforming growth factor-β) and it blocks tumor metastasis in vivo. The loss of DAPK mRNA M
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In LPS treated BV cells we found that the
2020-12-14

In LPS-treated BV-2 cells, we found that the upregulated CysLT2R was translocated into the nucleus. The nuclear localization of CysLT2Rs in microglia has not been reported previously. It is known that CysLT1Rs in endothelial hyPerFUsion™ high-fidelity DNA polymerase mg translocated to the nucleus i
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br Materials and methods br Results br Discussion In
2020-12-14

Materials and methods Results Discussion In this study, we investigated two novel candidate therapeutics, the related CRM1-inhibiting SINEs KPT-185 and KPT-276, in treatment of NHL. The results showed that KPT-185 induced growth inhibition, cell-cycle arrest, and apoptosis in tumor Losartan
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In this study we observed alterations in
2020-12-14

In this study, we observed alterations in mRNA levels of CRF receptors in the PFCx and Hip during the development of sensitization. In particular, in the Hip both CRF receptors showed significantly increased diluting solutions when the sensitization condition was established. Similarly, CRF2 recepto
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The best preserved individuals were selected for isotope
2020-12-14

The best preserved individuals were selected for isotope analysis of diet (Table 2). These represent 21 individuals including four subadults: two young children aged between 1.5 and 2.5 years old, one child between 7 and 11 years old and one adolescent (12–16 years old), and 17 adults including six
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Due to its several industrial
2020-12-14

Due to its several industrial applications, the recombinant production of collagen and all its derivatives as gelatins has been pursued for many years in different biological systems as mammalian cdc42 pathway (Toman et al., 1999), tobacco plants (Ruggiero et al., 2000), silkworms (Tomita et al., 2
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VHb expression in recombinant E coli expressing P H
2020-12-14

VHb expression in recombinant E. coli expressing P4H improved Hyp production, presumably by enhancing oxygen transfer. VHb expression contributed to improving growth and extending the period of exponential growth in both shaker flask culture and bioreactor fermentation. A similar phenomenon was also
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br Results br Discussion This study
2020-12-14

Results Discussion This study assesses impacts of HLA-DPB1 and CMV reactivation on GVHD, relapse, and OS after allo-HSCT. Here we demonstrate that HLA-DPB1 and CMV reactivation both increase aGVHD risk independently. Consistent with reported data, we show that HLA-DPB1 mismatching is associate
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br Introduction The cys loop ligand gated ion channels LGICs
2020-12-14

Introduction The cys-loop ligand gated ion channels (LGICs) are membrane-bound proteins mediating fast transduction from chemical to electrical signals at neuronal synapses and neuromuscular junctions [1], [2]. Each subunit that makes up the pentameric LGIC architecture possesses a dicysteine bri
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br Conflicts of interest br Acknowledgements This study was
2020-12-14

Conflicts of interest Acknowledgements This study was funded by Kuwait University Research Administration (Project MI03/10). Introduction Epidemiological, experimental and biologic plausibility support a cardioprotective effect of estrogens in women [1]. Indeed, women are protected until t
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In this study we also conducted
2020-12-14

In this study, we also conducted an analysis comparing the expression profiling of Hh genes among the sarcomas investigated. In these tumors, the IHH gene showed a higher expression level than PTCH1 gene in RMS and SS samples (pHeparin in human RMS cell lines as well as mouse NIH-3T3 fibroblasts. T
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