• br Materials and methods br Results br

  2021-04-17

  

  Materials and methods Results Discussion In general, CI symptoms are often visible only after the chilled products have been removed from coolstore to a warmer temperature (Schirra and Cohen, 1999). However, in the present work, 'satsuma’ mandarin fruit stored at 2°C showed chilling symptom

• Preclinical and clinical research indicates that inflammatio

  2021-04-17

  

  Preclinical and clinical research indicates that inflammation contributes to the progression of ICH injury. Therefore, there is a pressing need to develop interventions that can limit neuroinflammation and its detrimental effects on Tranilast function. Inflammatory cytokines are secreted in the bra

• br Materials and methods br Results

  2021-04-17

  

  Materials and methods Results Discussion NB has been shown to induce cancers in many tissues including the kidney, liver, and thyroid, following chronic inhalation in animals (Hsu et al., 2007). The available data indicate that a lager majority of studies on NB evaluate the effects of toxic

• br Materials and methods br Results br Discussion In

  2021-04-17

  

  Materials and methods Results Discussion In this study, we investigated two novel candidate therapeutics, the related CRM1-inhibiting SINEs KPT-185 and KPT-276, in treatment of NHL. The results showed that KPT-185 induced growth inhibition, cell-cycle arrest, and apoptosis in tumor Ro 3306

• The aim of the present study was to investigate the

  2021-04-17

  

  The aim of the present study was to investigate the participation of CRF1 and CRF2 in the alterations of the dorsal and ventral striatal dopamine release and the vertical and horizontal locomotor activity observed in rats following chronic nicotine treatment and consequent acute withdrawal. In this

• The CPA EoS was presented by Kontogeorgis et al

  2021-04-16

  

  The CPA EoS was presented by Kontogeorgis et al., in 1996 [23]. The proposed equation is composed of two parts (SRK EOS + association term) such that it can well predict the thermodynamic behavior of hydrogen bonding materials as a result of considering the association term. Yakoumis et al. (1997) e

• Alzheimer s disease AD is

  2021-04-16

  

  Alzheimer’s disease (AD) is a chronic, progressive neurodegenerative disorder of the the black and white film which is considered a leading cause of dementia and affects 20–30 million people worldwide. Presently, a suitable treatment and prevention strategy against AD is hardly available. Various s

• In the present study the A P

  2021-04-16

  

  In the present study, the A/P ratio in the MCF-7 cell line was significantly increased by the combination of 1 nM E2 and progestogens, except P4, as well as by10 nM E2 combined with NET. The similar findings were also noted by several reports [16], [17], [18], [19], [20] in which progestogens combin

• br Effects of estrogens on

  2021-04-16

  

  Effects of estrogens on bone Estrogens play an important role in bone remodeling, as demonstrated by studies in mice in which the ER genes were deleted [21], [22]. ERβ compensates for the Mifepristone of ERα, and vice versa, but when both ERs are deleted a profound decrease in trabecular bone vol

• trpv1 antagonist As a co factor CIITA

  2021-04-16

  

  As a co-factor, CIITA lacks the ability to recognize and directly bind to specific DNA elements to regulate transcription; instead, it relies on interaction with sequence-specific transcription factors (TFs) to be recruited to the chromatin. Therefore, the observation that CIITA binds to a specific

• VMD v Humphrey et al was used

  2021-04-16

  

  VMD v1.9.2 (Humphrey et al., 1996) was used to analyze the MD trajectories, salt bridge interactions and secondary structure information from each frame. Once the model was optimized, the topological diagram and area and volume of protein cavities were analyzed using PDBsum (Laskowski, 2009) and CAS

• br Acknowledgements This work was financially supported

  2021-04-16

  

  Acknowledgements This work was financially supported by Industrial Technology Institute, Sri Lanka through funds received from Sri Lankan Government Treasury (TG13/69). G. D. Liyanaarachchi received postgraduate research scholarship grant from National Science Foundation Sri Lanka (NSF/SCH/2017/0

• br Roles of DDR in epithelial

  2021-04-16

  

  Roles of DDR1 in epithelial cell differentiation Roles of DDR1 in cell migration, and invasion Dichotomous functions of DDR1 in disease progression Conclusions and perspectives The switch in DMOG from DDR1 to DDR2 during EMT is another important issue. The DDRs may exert distinct or red

• Our study found a significant association

  2021-04-16

  

  Our study found a significant association between the degree of primary tumor lobulation and EGFR mutations status (P EGFR KU55933 receptor status. However, only a small portion of these previous studies included the evaluation of lobulation, and almost all of them reported no association between E

• Exposure to ultraviolet radiation with sunlight is generally

  2021-04-16

  

  Exposure to ultraviolet radiation with sunlight is generally accepted as the major cause of basal-cell carcinoma (Gallagher et al., 1995). The risk of this disease is significantly increased by age. Skin cancers are the most common tumours of the head and neck region and their prevalence shows progr

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