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Interpretation Patient centred medical education
2019-06-25

Interpretation Patient-centred medical education can improve overall satisfaction and sustained disease-specific knowledge in patients in Uganda. Our results show that printed booklets are accepted by patients and feasible to implement in a LMIC outpatient setting. Funding Trishul Siddharthan recei
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Introduction Classically increased cardiac fibrosis has been
2019-06-25

Introduction Classically, increased cardiac fibrosis has been shown to be associated with altered cardiac conduction, causing conduction slowing, block, and reentry in studies on isolated animal and diseased human cardiac tissues [1–3]. Interestingly, similar findings were also demonstrated in isol
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br Discussion Primary lymphoma of bone is a rare
2019-06-25

Discussion Primary lymphoma of bone is a rare disease, first described by Oberling in 1928 and he labeled it as reticulum cell sarcoma of bone because of the presence of characteristic reticulin fibers within the lesion [5]. This work was followed by Parker and Jackson and later by Ivin and Bosto
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A recent meta analysis has shown that an
2019-06-25

A recent meta-analysis has shown that an enlarged LA increases the risk of AF recurrence after a single CPVI, regardless of the follow-up duration [5]. This finding can be applied to paroxysmal and persistent AF [6,7]. In clinical practice, measurement of LAD can provide a window into the status of
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HIV counselling and testing is the
2019-06-25

HIV counselling and testing is the essential first step to accessing HIV care services and is also recognised as an HIV prevention strategy because knowledge of HIV status reduces risky sexual behaviours. A reduction in the number of sexual partners has been reported, but not a significant increase
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IRAK-1-4 Inhibitor I of En M xico el folclor nacionalista
2019-06-25

En México, el folclor nacionalista de los siglos xix y xx matizó la tipificada creencia cultural de la “convivencia natural” del mexicano con la muerte para explicar y sobrellevar, incluso de manera socarrona, los estragos económicos y sociales del destino mexicano. Elsa Malvido, en este sentido, en
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Diversos trabajos coinciden en mencionar el impacto positivo
2019-06-25

Diversos trabajos coinciden en mencionar el impacto positivo que la auh ha tenido en términos de inclusión y justicia social frente LX-1031 of la situación donde sólo había asignación familiar contributiva, a partir de variables macroeconómicas como la modificación de tasas de pobreza e indigencia,
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HF is associated with the
2019-06-25

HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th
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Introduction By catalyzing post translational acetylation of
2019-06-24

Introduction By catalyzing post-translational acetylation of lysine residues, the histone acetyl transferases (HAT) CREBBP and EP300 moderate the activities of both histone and non-histone proteins. This regulates vital cellular processes such as cell cycling and apoptosis by modulating chromatin s
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Of note gender equity might continue despite the economic de
2019-06-24

Of note, gender equity might continue despite the economic development of a society. Studies by Nussbaum and Sen have shown no direct relation between wealth and equity. Hence, some countries with high wealth, such as Saudi Arabia, also a have high degree of gender inequity, whereas others with low
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Accordingly blockade of TL A Fas L TLR cascades and
2019-06-24

Accordingly, blockade of TL1A/Fas-L/TLR4 cascades and inhibition of the M1/Th1 differentiation associated with DcR3 might potentially rescue hepatic IR injury. However, the contribution of TL1A/Fas-L/TLR4 on the M1/M2 and Th1/Th2 balances, as well as pathogenic liver IR injury had never previously b
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The CONNECT trial conducted by
2019-06-24

The CONNECT trial conducted by Crossley et al. [22] was also a multicenter, prospective, randomized evaluation of wireless RM, which included 1997 patients implanted with ICDs or CRT-Ds. They were randomly assigned to the remote or in-office groups and followed up for 15 months. The median time fro
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Introduction Paraneoplastic immune mediated encephalopathy
2019-06-24

Introduction Paraneoplastic immune-mediated encephalopathy is a newly described disease. In 2005, Vitaliani et al first reported that four young women with ovarian teratoma (OT) had developed acute psychiatric and neurologic symptoms, e.g., seizures, memory deficits, decreased level of consciousnes
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Both breast cancer and MM cause osteolytic
2019-06-24

Both breast cancer and MM cause osteolytic lesions, inhibiting osteoblast differentiation and thereby tipping the balance in favour of osteoclastic activity. In contrast, prostate cancer predominantly causes osteoblastic bone disease. Interestingly, increased marrow adiposity has been associated wit
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The beats with high amplitude
2019-06-24

The beats with high-amplitude J wave with short preceding DIs induced low systolic blood pressure, indicating weak cardiac contractility due to decreased calcium influx through I and calcium release during ventricular systole. In contrast, the beats with low-amplitude J wave preceded by long DIs ind
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