Archives
- 2025-10
- 2025-09
- 2025-03
- 2025-02
- 2025-01
- 2024-12
- 2024-11
- 2024-10
- 2024-09
- 2024-08
- 2024-07
- 2024-06
- 2024-05
- 2024-04
- 2024-03
- 2024-02
- 2024-01
- 2023-12
- 2023-11
- 2023-10
- 2023-09
- 2023-08
- 2023-07
- 2023-06
- 2023-05
- 2023-04
- 2023-03
- 2023-02
- 2023-01
- 2022-12
- 2022-11
- 2022-10
- 2022-09
- 2022-08
- 2022-07
- 2022-06
- 2022-05
- 2022-04
- 2022-03
- 2022-02
- 2022-01
- 2021-12
- 2021-11
- 2021-10
- 2021-09
- 2021-08
- 2021-07
- 2021-06
- 2021-05
- 2021-04
- 2021-03
- 2021-02
- 2021-01
- 2020-12
- 2020-11
- 2020-10
- 2020-09
- 2020-08
- 2020-07
- 2020-06
- 2020-05
- 2020-04
- 2020-03
- 2020-02
- 2020-01
- 2019-12
- 2019-11
- 2019-10
- 2019-09
- 2019-08
- 2019-07
- 2019-06
- 2019-05
- 2019-04
- 2018-07
-
br Concluding remarks Some of
2019-07-15
Concluding remarks Some of the clinical trials of putative neutral competitive ERAs have been less successful than anticipated 6, 8, 11. This might be because of underestimation of the complexity of the molecular pharmacology of ETA. To resolve this, it will be necessary to define the signaling m
-
Hordenine br Discussion Variable estradiol effects on cell p
2019-07-15
Discussion Variable estradiol effects on cell proliferation have been reported according to animal species, tissues, and type of estrogen receptor [16,21,22,[29], [30], [31]]. In the kidney, 17βE was found to increase [3H]-thymidine incorporation in primary rabbit kidney proximal tubule Hordenine
-
Introduction Proteins play an important role in cellular fun
2019-07-15
Introduction Proteins play an important role in cellular functions; however, being and remaining properly folded is necessary for their function. Understanding the stability of the protein is necessary to investigate the folding of proteins, as well as their conformation, functions and interactions
-
In this study we have
2019-07-15
In this study we have explored a functional role of the oxysterol/EBI2 system in this process. In 2011 we and others reported the discovery of oxysterols as ligands for EBI2 [6], [7]. Oxysterols are metabolites generated by hydroxylation of cholesterol and have been linked to a variety of fundamenta
-
Compounds were synthesized using a facile step
2019-07-15
Compounds were synthesized using a facile 8-step convergent synthesis ( and ). Briefly, (Boc)cyclen (compound ) was coupled using TBTU to Fmoc- or Cbz-protected amino alkyl acids (–), followed by deprotection using 20% piperidine in DMF, or H on Pd/C, respectively (–) (). Deprotected linkers were co
-
VX-745 Our results indirectly support the combination
2019-07-13
Our results indirectly support the combination of resveratrol and hesperatin treatment for PDN, as this induces GLO1 activity in patients (Xue et al., 2016), as well as metformin, an FDA-approved anti-diabetic treatment, which acts as an MG scavenger to reduce MG levels in type 2 diabetic patients (
-
Obviously there are some limitations in
2019-07-13
Obviously, there are some limitations in our study; due to sample constraints, we had to focus our efforts on one specific T cell epitope from one candidate autoantigen. Optimally, we could have studied several different peptides in parallel. Additionally, all RA patients included in the study have
-
2-NBDG what br Materials and methods br Results br Discussio
2019-07-13
Materials and methods Results Discussion Approximately 90% of pulmonary emphysema causes are related to smoking and its progression in patients and are characterized by severity levels [5]. Experimental models using CS to induce emphysema are widely used because they resemble the emphysema
-
The hepatic constitutive levels of CYP
2019-07-13
The hepatic constitutive levels of CYP1A2 were minimal and were below detectable limits in the kidney, indicating an organ-specific trend which has been reported by other groups (Hawke and Welch, 1985, Paolini et al., 1997, Parkinson, 1996, Villard et al., 1998). Retinol administration did not have
-
br Methods br Results br Discussion On the other
2019-07-13
Methods Results Discussion On the other hand, surgical patients have to some extent stress during pre- and/or post-operative period. It is well known that CRF/CRF1 receptor is involved in the activation of HPA during acute and chronic stress (Papadimitriou and Priftis, 2009, Zelena et al.,
-
br Study br Study meta analyses br Discussion Ten studies
2019-07-13
Study 1 Study 2: meta-analyses Discussion Ten studies have examined the associations of 5-HTTLPR and COMT Val158Met with alexithymia. However, the findings were mixed. In this study, we found that neither the 5-HTTLPR nor COMT Val158Met is associated with alexithymia. The previous findings
-
The data in our manuscript confirm previous data
2019-07-13
The data in our manuscript confirm previous data on the origin of CMV-specific T proton pump inhibitor following TCD alloSCT in CMV seropositive patients transplanted with a CMV seronegative donor (R+D−) and demonstrate that also recipient CMV-specific memory T-cells are able to survive alemtuzumab
-
The second part of this study evaluated
2019-07-13
The second part of this study evaluated the role of CK1 in the eFABP4 cellular uptake in endothelial cells. By blocking CK1 expression using a specific siRNA, we corroborated that the presence of CK1 was fundamental for FABP4 cellular uptake and internalization in endothelial cells, thus decreased m
-
Significantly elevated levels of DNA damage observed in peri
2019-07-13
Significantly elevated levels of DNA damage observed in peripheral blood of tea garden women workers indicate the occupational exposure. The same was observed in cholinesterase activities, which detected lower activity in the exposed group compared to non-exposed. Large volumes of pesticides are use
-
br Conclusions Two chemical coupling agents BTDE
2019-07-13
Conclusions Two chemical coupling agents, BTDE and CDI, were used to activate the free hydroxyl groups of plant cellulose powder and OPH from Flavobacterium ATCC 27551 immobilized on modified carriers by covalent linkages. The highest immobilization yields obtained in optimum conditions of effect
16053 records 1025/1071 page Previous Next First page 上5页 10211022102310241025 下5页 Last page