• Examples of numerically generated vortices and their organiz

  2019-05-08

  

  Examples of numerically generated vortices and their organizing centers in 3-D excitable media are illustrated in Fig. 1. Panels a to d show 4 different configurations of 3-D scroll waves that were computed using the FitzHugh–Nagumo model [39,40]. Panel a shows an example of the simplest configurati

• Introduction Personalized medicine is the major goal of tran

  2019-05-08

  

  Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease ion channels and predict clinical outcome. However, to define a specific disease phenotyp

• Introduction Osteosarcoma OS is the most common type

  2019-05-08

  

  Introduction Osteosarcoma (OS) is the most common type of bone tumor occurred in adolescents and children [1]. OS is highly malignant and accounts for about half of bone sarcomas with high potential of metastasis [2]. Treatment for OS is mainly depended on surgical operation, assisted with chemothe

• Implementation of contemporary treatment protocols

  2019-05-08

  

  Implementation of contemporary treatment protocols, incorporating adjuvant chemotherapy, have resulted in an improvement in the prognosis of patients diagnosed with osteosarcoma over the past decades. The overall 5-year survival rate has improved from less than 20% in the 1960s to approximately 60%

• La mayor parte de las actividades del movimiento durante

  2019-05-07

  

  La mayor parte de las actividades del movimiento durante los meses siguientes se dedicó her2 inhibitor la recaudación de fondos con destino a financiar las actividades de insurrección en el interior de España. En este sentido, se orientaron actividades tales como la creación de un grupo de teatro ex

• The coverage and quality of laboratory services throughout A

  2019-05-07

  

  The coverage and quality of laboratory services throughout Africa is inadequately documented. Quality provided by individual laboratories is questioned, and not all facilities are enrolled in external quality assurance schemes. For example, in 2013, an evaluation of accredited laboratories in sub-Sa

• Mechanistic target of rapamycin mTOR a highly conserved

  2019-05-07

  

  Mechanistic target of rapamycin (mTOR), a highly conserved serine-threonine protein kinase, is a key regulator of cell growth and metabolism. As discussed above, mTORC1 is a negative regulator of the preinitiation complex that modulates the initiation of autophagosome biogenesis. Pharmacological and

• The primary outcome was local

  2019-05-07

  

  The primary outcome was local recurrence or metastasis. The secondary outcome included functional outcome based on Musculoskeletal Tumor Society (MSTS) score. Data for the study were retrieved from hospital records, maintained oncological files, surgical files, and clinical examination at the most r

• br Introduction Patients with advanced breast prostate

  2019-05-07

  

  Introduction Patients with advanced breast, prostate, lung and colo-rectal cancer frequently develop bone metastases (BMs). These lesions may be asymptomatic or may cause pain, pathologic fractures, malignant hypercalcemia, epidural spinal cord compression and/or shorten survival [1]. The underly

• Blebbistatin Close inspection of the tumor matrix on the ini

  2019-05-07

  

  Close inspection of the tumor matrix on the initial and subsequent 5 month radiographs (Fig. 7), shows an atypical appearance for osteoid matrix that Blebbistatin may more closely resemble chondroid matrix. The matrix appears to display a linear dense lace-like pattern (Fig. 8). Of the only two oth

• Introduction Metastasis to the bone is

  2019-05-07

  

  Introduction Metastasis to the bone is a common complication of breast, lung, prostate, gastrointestinal, haematological, melanoma, and other tumours [1–3]. In many patients with primary breast, prostate and lung primary tumours, bone metastases (BoM) are signs associated with the presence of disse

• Cryotherapy related soft tissue injury usually occurs within

  2019-05-07

  

  Cryotherapy related soft tissue injury usually occurs within a few weeks postoperatively. Skin necrosis is a significant complication if freezing of the superficial surface occurs. Constant irrigation of the adjacent tissues with warm saline reduces the chance of skin necrosis. Our rate of infection

• LQT can have numerous clinical manifestations ranging from n

  2019-05-07

  

  LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise

• pyrilamine maleate Estes exemplos s o iniciativas

  2019-05-07

  

  Estes exemplos são iniciativas importantes para termos um esboço da relação entre pyrilamine maleate Igreja católica e a política no Brasil durante primeiras décadas do século xx. Elas denotam certo poder de resistência da instituição frente a possíveis ameaças de sua hegemonia como provedora de um

• br Una de las m s acres y reiteradas recriminaciones

  2019-05-07

  

  Una de las más acres y reiteradas recriminaciones topoisomerase inhibitor la tl provenientes de los sectores eclesiales más conservadores, ha estado fundada en el uso del instrumental teórico de origen marxista y su tesis de la lucha de clases, debido a que se le atribuye una irreconciliable incom

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