• It must be noted that modern physical techniques for

  2019-05-24

  

  It must be noted that modern physical techniques for structural analysis of steroids were not available to these early talented scientists that time. It was a challenging task for these early scientists to precisely identify the chemical structures of cholesterol and bile acids. However, the develop

• br El nacionalismo entendido como una

  2019-05-24

  

  El nacionalismo, entendido como una ideología y un movimiento político-social, aparece con el concepto moderno de la nación como respuesta calcifediol una necesidad urgente de legitimar el nuevo orden político-social republicano, en el que la “soberanía del pueblo” reemplazaba al “derecho divino”

• br ALANISMO E IZQUIERDA UNIDA No plano pol tico o

  2019-05-24

  

  ALANISMO E IZQUIERDA UNIDA No plano político, o desmoronamento da iu está associado às ambiguidades com que se relacionou com a primeira força política do país neste momento, o apra e o presidente Alan García. Especificamente, o grupo em torno de Alfredo Barrantes acreditou em um cenário de alter

• On Aug WHO quietly released a report

  2019-05-24

  

  On Aug 23, WHO quietly released a report that should be essential reading for all. Coming 15 years after the Abuja Declaration by African governments to commit to spending 15% of annual domestic budgets on health, concludes with a stark analysis: “For every US$100 that goes into state coffers in Af

• O quilombo caracterizado como uma associa o guerreira aberta

  2019-05-23

  

  O quilombo é caracterizado como uma associação guerreira aberta, sem distinção de linhagens e transcultural. A transculturalidade vem das contribuições de povos distintos, com destaque para os imbangala. No ritual de iniciação dos imbangala, cathepsin inhibitors circuncisão representava o rito de pa

• Class IC antiarrhythmic drugs such as

  2019-05-23

  

  Class IC antiarrhythmic drugs such as pilsicainide and propafenone have been used to terminate or prevent ATs, particularly atrial fibrillation [15–17]. Pilsicainide and propafenone in Japan, and ajmaline in Europe, are commonly used as first-line drugs for antiarrhythmic therapy [13]. We often enco

• Aggressive osteoblastoma is characterized by epithelioid

  2019-05-23

  

  Aggressive osteoblastoma is characterized by epithelioid osteoblasts that are, two to three times larger than conventional osteoblasts, and have abundant eosinophilic cytoplasm, large vesicular eccentric round to oval nuclei with prominent nucleoli. Usually there are rare or absence of mitoses and i

• At least genes are associated with familial LQTS with

  2019-05-23

  

  At least 15 genes are associated with familial LQTS, with 3 of these genes accounting for 70–75% of cases [5]. Despite advances in the understanding of the molecular basis of LQTS, challenges remain in making the clinical diagnosis. Importantly, between 10–40% of gene carriers have normal QT interva

• The region is also suffering from

  2019-05-23

  

  The region is also suffering from administrative negligence, extreme poverty, lack of basic health facilities, and weak infrastructure, which have increased its vulnerability to the climatic misery. Travel time to the nearest health facility is 2–4 h, at a cost of PKR 1000–4000 (US$10–40) in a regio

• br Discussion A familial platelet disorder with a

  2019-05-23

  

  Discussion A familial platelet disorder with a propensity to myeloid malignancy (FPD/MM) was first reported in 1978 and since then approximately 30 pedigrees with RUNX1 germline mutations have been reported in the literature [9,11]. The RUNX1 gene is composed of 10 exons (1–6, 7A, 7B, 7C and 8).

• br Ogolpe militar do dia de

  2019-05-22

  

  Ogolpe militar do dia 11 de setembro de 1973, no Chile, destituiu do poder o então presidente Salvador Allende, eleito em 1970 pela Unidad Popular (up), coalizão política composta por partidos de esquerda que propunham U 73343 “via chilena para o socialismo”. De acordo com Priscila Carlos Brandão

• br Relationship among ICD shocks substrate

  2019-05-22

  

  Relationship among ICD shocks, substrate, and mortality There is a strong correlation between ICD-shocked spontaneous VTAs and subsequent mortality [5,6]. Patients who receive inappropriate shocks are also at an increased risk of mortality, although the magnitude of this increase is smaller [5,6]

• br Conflict of interest statement br Acknowledgments Funded

  2019-05-22

  

  Conflict of interest statement Acknowledgments Funded by the Division of Medical Oncology at Princess Margaret Hospital, Toronto, Canada. No pharmaceutical company funding was received. The authors acknowledge the roles of Esther Lee and Tazmin Usmani in trial coordination and Dr. Ranjeeta Mal

• br Discussion br Conclusions br Conflicts of interest br

  2019-05-22

  

  Discussion Conclusions Conflicts of interest Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is induced by emotional stress or exercise in patients without organic heart disease and may be polymorphic or bidirectional (Fig. 1) [1–3]. This ventricular arrhythmia

• The WHO Safer Primary Care report has grappled

  2019-05-22

  

  The WHO Safer Primary Care report has grappled head-on with the challenges associated with many variations in the scope, nature, and provision of primary care in different countries; insufficient data from low-income and middle-income country settings to inform priorities for care; the need to devel

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