• The importance of the microenvironment for cancer

  2019-06-05

  

  The importance of the microenvironment for cancer development and progression is now widely recognised, but it is worth reminding ourselves that this is a relatively young area of research. Anyone searching PubMed today using the terms “” will find over 22,000 scientific publications, with around 30

• UNC 0642 br Conclusion br Conflict of interest

  2019-06-05

  

  Conclusion Conflict of interest Case report A 65-year-old woman with permanent atrial fibrillation was admitted with diastolic UNC 0642 failure (HF) secondary to rapid ventricular response. She had undergone single chamber pacemaker implantation (Boston Scientific Ingenio SR) two years earl

• La sensaci n de desmoronamiento y de v rtigo nace

  2019-06-05

  

  La sensación de desmoronamiento y de vértigo nace en “Lumbre en el aire” de la confusión de lo terrestre con lo estelar o sideral. Mientras los signos “jardines”, “mar” o “rocas” remiten a realidades telúricas, “cielo”, “astros”, “cometas”, “aerolitos” “galaxia” sitúan al lector en la dimensión cósm

• Vaccines for rotavirus and cholera the two

  2019-06-05

  

  Vaccines for rotavirus and cholera—the two diseases with the highest child mortality rates and a significant fraction of the global diarrhoeal burden—are at preliminary stages of implementation. The use of vaccination as a global primary-prevention strategy can also be rapidly strengthened with the

• O efeito mim tico das pr ticas

  2019-06-05

  

  O efeito mimético das práticas exercidas pela Igreja Universal teve impacto substancial no campo religioso, influenciando inclusive instituições fora do neopentecostalismo. Por exemplo, mediante este processo, a Igreja católica redobrou esforços para ampliar seu capital político. Neste caso, Emerson

• br Conclusion br Authors contribution

  2019-06-05

  

  Conclusion Authors’ contribution Competing interests Acknowledgments Case report Imatinib has radically changed prognosis in chronic-phase Chronic Myeloid Leukemia (CML), with 90% overall survival rate at 8yrs, and 40–70% of patients achieving a stable MMR [1]. Even better results hav

• African leaders are gathering in Addis Ababa Ethiopia

  2019-06-05

  

  African leaders are gathering in Addis Ababa, Ethiopia, this week for the first ever . The event brings together government officials, including minsters of finance, technical experts, and policymakers, with the goal of advancing the coverage of life-saving immunisations across the continent. In

• To determine the discriminatory power of the

  2019-06-05

  

  To determine the discriminatory power of the ischiopubic index, the ROC curve was used (Fig. 3). The area under the curve for sex differentiation was 83.5% for the ischiopubic index. In the study phospholipase a2 inhibitor with a differentiation point of 100.47°, sensitivity of 82%, specificity of 7

• Desde mediados de la d cada de los sesenta la

  2019-06-01

  

  Desde mediados de la década de los sesenta, la embajada argentina pedía informes sobre las actividades políticas en general y sobre las consideradas subversivas en Guatemala. A juicio de la embajada, en 1978 no se podía analizar la “ola de violencia” en Guatemala sin incluirla en el contexto de lo q

• Adequate nutritional support for pregnant women

  2019-06-01

  

  Adequate nutritional support for pregnant women is an important issue, not only to help such women maintain peak health and performance, but also as it indirectly affects fetal growth and the minimization of adverse fetal outcome risks. Among those nutritional components that are integral to this su

• br Historical overview Before the development of screw in le

  2019-06-01

  

  Historical overview Before the development of screw-in leads, several types of non-screw pacing leads were designed to passively attach to the handbag muscle with tips of different shapes, including straight, fringed, finned, or tined. However, a high incidence of dislodgement was a major concer

• Any abnormality causing a loss of function in

  2019-06-01

  

  Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -

• orexin a Sin considerar la poes a de Villaurrutia en esta

  2019-06-01

  

  Sin considerar la poesía de Villaurrutia en esta ocasión, es evidente que el pasaje citado representa una elocuente cristalización del su relevancia para el pensamiento y la poética de Octavio Paz. Es notable que el juicio crítico de Paz incluya referencias al universo —donde los opuestos coexisten

• De esta poca son los primeros testimonios de la idea

  2019-06-01

  

  De esta época son los primeros testimonios de la idea de fundar un periódico en París: en una carta del 7 de agosto de 1848, Eugène Carpentier, futuro administrador de La Tribune des Peuples, le presenta THZ1 Hydrochloride Mickiewicz un presupuesto estimado de lo que costaría un periódico. De cualqu

• A possible mechanism of the initiation of HSTCL

  2019-06-01

  

  A possible mechanism of the O4I1 manufacturer of HSTCL is a prolonged immunosuppressive status which generates the expansion of γδ T-cells recognizing multiple pathogens through excessive antigenic stimulation. Our cases did not have any previous illness related to immunosuppression, recurrent infec

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