• The tumor microenvironment is enriched

  2019-06-15

  

  The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma

• br Results There were cases

  2019-06-15

  

  Results There were 232 cases where cryotherapy was used in 214 patients between 1994 and 2015. There were 96 male and 118 female. The age of patients ranged from 4 to 95. All patients had undergone imaging studies for evaluation. A majority of cases consisted of active or aggressive benign tumors

• This patient had sick sinus syndrome and

  2019-06-15

  

  This patient had sick-sinus syndrome and also took sotalol for the prevention of VT related to ARVC. Therefore, constant atrial pacing was indispensable for maintaining a physiological atrial rhythm. Frequent right ventricular pacing is known to cause left ventricular dysfunction, myocardial perfusi

• br In mid close to the finish

  2019-06-15

  

  In mid-2015, close to the finish line of the Millennium Development Goals (MDGs), Tanzania has reason to be proud. As Hoviyeh Afnan-Holmes and colleagues note in their Countdown to 2015 case study, Tanzania is on track to achieve MDG4: a two-thirds Ramelteon in child mortality. The largest gains

• El sujeto de la enunciaci

  2019-06-15

  

  El sujeto de la enunciación se subordina nvp-aew541 la autoridad y dominio del príncipe y, por interpósita persona del rey, como súbdito y leal servidor: “[…] tuve por conveniente servir a vuestra alteza con este sumario brevísimo de muy difusa hystoria que de los estragos e perdiciones acaecidas se

• En tanto fray Bartolom de las Casas resume el breve

  2019-06-15

  

  En tanto, fray Bartolomé de las Casas resume el breve pasaje inicial de Pané en el capítulo cxx del volumen I de la Apologética Historia: Deidades, ídolos y cuerpos: el fracaso de pané El proyecto de construcción del monoteísmo taíno invalida la consistencia etnográfica del material recogido por

• Menci n aparte merecen dos rasgos en la construcci n

  2019-06-15

  

  Mención aparte merecen dos rasgos en la construcción de este personaje y de su entorno: en primer lugar, sufre de una úlcera en mi2 el duodeno que lo hace beber leche en múltiples momentos o mitigar el dolor masticando antiácidos Pepsamar. Mattos se está consumiendo por dentro, en una metáfora que u

• br Should child growth replace diarrhoea

  2019-06-14

  

  Should child growth replace diarrhoea as the primary child health outcome for sanitation trials? We appreciate Derek Headey\'s comment in relation to our trial that the window of opportunity to plausibly affect growth faltering is from in utero up to 24 months, and therefore that sanitation trials

• br Conclusions br Disclosures br Introduction

  2019-06-14

  

  Conclusions Disclosures Introduction Since their introduction, at the end of fifties, cardiovascular implantable devices (CIEDs) have widely expanded in number and in their functions [1,2]. The dramatic increase in the number of CIEDs implanted in the last decade is mainly due to the aging

• br Case report A year old female presented

  2019-06-14

  

  Case report A 50-year-old female presented with splenomegaly (24 cm) and pancytopenia in Mar. 2014. A bone marrow biopsy revealed hypocellular marrow (1st order MRS 2578 of R-COP (Fig. 3). Further 5 cycles of cytotoxic therapy with standard dose R-CEOP (rituximab; cyclophosphamide; epirubicin;

• Since many decades bone tumours have stimulated

  2019-06-14

  

  Since many decades, bone tumours have stimulated imagination of researchers and numerous therapeutic alternatives have been proposed [134,135, Fig. 4]. The better knowledge of OPG/RANK/RANKL system leads to the development of peptides mimicking OPG and blocking RANK–RANKL interactions [136–139]. Inh

• Teniendo en cuenta la labor de traducci

  2019-06-14

  

  Teniendo en cuenta la labor de traducción cultural que estos letrados criollos inician en Europa y que piensan como puente de transformaciones culturales y políticas para el espacio americano, analizaremos la traducción que realizan Rodríguez y Mier de la novela Atala de Chateaubriand en el año de 1

• br is a bacterial infection causing

  2019-06-14

  

  is a bacterial infection causing necrotising lesions of skin and subcutaneous tissue. Widely known as Buruli ulcer, it is classified as a neglected tropical disease by WHO. If diagnosed and treated early, outcomes are good, but if left untreated it can progress to a severe disease resulting in hig

• Almost all the information we have on clinical epidemiology

  2019-06-13

  

  Almost all the information we have on clinical epidemiology of patients with g calculator failure is collected in North America or in western European countriesTherefore, the work of Hisham Dokainish and colleagues in this issue of , is very welcome. Their study provides a clear picture of clinical

• br Pathophysiology and risk factors Patient

  2019-06-13

  

  Pathophysiology and risk factors Patient with CIED may get infected at time of initial molecular weight mg or during pocket revision for device change or upgrade [8,2]. Device erosions are by default infected but most commonly are a secondary manifestation of slow growing underlying infection [8

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